NCOR2 抗体
Quick Overview for NCOR2 抗体 (ABIN5701136)
抗原
See all NCOR2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NCOR2 antibody
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免疫原
- nuclear receptor co-repressor 2
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
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别名
- NCOR2
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背景
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Synonyms: Nuclear receptor corepressor 2 (N-CoR2)|CTG repeat protein 26|SMAP270|Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT)|T3 receptor-associating factor (TRAC)|Thyroid-, retinoic-acid-receptor-associated corepressor|NCOR2|CTG26
Background: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center(GC) reactions, mainly through the control of the GC B-cells proliferation and survival.
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分子量
- 180 kDa
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基因ID
- 9612
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UniProt
- Q9Y618
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途径
- Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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